Bioinformatics research papers

One significant advance in m 6 a research is the recent discovery of the first two m 6 a rna demethylases fat mass and obesity-associated (fto) gene and alkbh5, which catalyze m 6 a demethylation in an α-ketoglutarate (α-kg)- and fe 2+ -dependent manner. With the development of genomics and bioinformatics, especially the extensive applications of high-throughput sequencing technology, more transcriptional units with little or no protein-coding potential have been discovered. Modified mean gray wolf optimization approach for benchmark and biomedical er singh, sb ionary bioinformatics 2017:13 al research | published on 11 sep d steroids and active smoking drive chronic obstructive pulmonary disease symptoms and biomarkers to a greater degree than airflow e silkoff, dave singh, j mark fitzgerald, andreas eich, andrea ludwig-sengpiel, geoffrey c chupp, vibeke backer, celeste porsbjerg, pierre-olivier girodet, mark t dransfield, frederic baribaud, vedrana s susulic, matthew j ker insights 2017:12 al research | published on 07 sep chical association coefficient algorithm: new method for genome-wide association ionary bioinformatics 2017:13 al research | published on 31 aug : a software tool for identifying sophisticated 3-way interactions from cancer expression li bandyopadhyay, veda chanda, yupeng informatics 2017:16 ology | published on 28 aug oitin sulfate inhibits monocyte chemoattractant protein-1 release from 3t3-l1 adipocytes: a new treatment opportunity for obesity-related inflammation?

We also offer rss feeds which provide timely updates of tables of contents, newly published articles and calls for ational journal of bioinformatics research and applications (37 papers in press). Informatics 2017:16 ology | published on 18 aug ker: identifying phylogenetic markers at the population -mien ke, chun-ping yu, yu-ching liu, isheng j ionary bioinformatics 2017:13  | published on 16 aug ed-based graphics processing unit cluster platform for multiple sequence -da wei, hui-jun cheng, chun-yuan lin, jin ye, kuan-yu ionary bioinformatics 2017:13  | published on 08 aug le testing in the context of gene discovery in sickle cell disease using genome-wide association cs insights 2017:10  | published on 01 aug tency and variability of dna methylation in women during puberty, young adulthood, and chen, nandini mukherjee, vimala devi janjanam, s hasan arshad, ramesh j kurukulaaratchy, john w holloway, hongmei zhang, wilfried cs & epigenetics 2017:9 al research | published on 28 jul -oncology integrative networks: elucidating the influences of osteosarcoma sharma, enrico informatics 2017:16 al research | published on 26 jul -in-flux-expressions methodology: toward a robust mathematical framework for quantitative systems pharmacology t mcquade, ruth e abrams, jeffrey s barrett, benedetto piccoli, karim regulation and systems biology 2017:11  | published on 26 jul e nearest neighbor search on a protein-protein interaction network to infer protein-disease t suratanee, kitiporn ormatics and biology insights 2017:11 al research | published on 13 jul tion with dimension reduction of multiple molecular data sources for patient kaplan, eric f informatics 2017:16 ology | published on 11 jul fication of very small open reading frames in the genomes of holmes jungle virus, ord river virus, and wongabel virus of the genus , gubala, susan walsh, jane mcallister, richard weir, steven davis, lorna melville, ian mitchell, dieter bulach, penny gauci, alex skvortsov, david ionary bioinformatics 2017:13  | published on 11 jul impact of collisions on the ability to detect rare mutant alleles using barcode-type next-generation sequencing vanliere canzoniero, karen cravero, ben ho informatics 2017:16 al research | published on 10 jul ts into signaling in cell-based therapy for heart c rieger, bryon a tompkins, monisha banerjee, makoto natsumeda, victoria florea, ivonne h transduction insights 2017:6  | published on 10 jul assessment of database-validated microrna target genes in normal colonic mucosa: implications for pathway l slattery, jennifer s herrick, john r stevens, roger k wolff, lila e informatics 2017:16 al research | published on 23 jun stic impact of urokinase plasminogen activator receptor expression in pancreatic cancer: malignant versus stromal a wl de geus, victor m baart, martin c boonstra, peter jk kuppen, hendrica ajm prevoo, andrew p mazar, bert a bonsing, hans morreau, cornelis jh van de velde, alexander l vahrmeijer, cornelis fm ker insights 2017:12  | published on 22 jun 2017. Quantitative systems pharmacology platform to investigate the impact of alirocumab and cholesterol-lowering therapies on lipid profiles and plaque y e ming, ruth e abrams, derek w bartlett, mengdi tao, tu nguyen, howard surks, katherine kudrycki, ananth kadambi, christina m friedrich, nassim djebli, britta goebel, alex koszycki, meera varshnaya, joseph elassal, poulabi banerjee, william j sasiela, michael j reed, jeffrey s barrett, karim regulation and systems biology 2017:11 al research | published on 22 jun meaningful clinical use of w j selleck, maheswari senthil, nathan r ker insights 2017:12  | published on 19 jun t: a web tool for the co-expression analysis of brassica rapa kim, kyong mi jun, joung sug kim, songhwa chae, yoon-mok pahk, tae-ho lee, soo-in sohn, soo in lee, myung-ho lim, chang-kug kim, yoonkang hur, baek hie nahm, yeon-ki ionary bioinformatics 2017:13 al research | published on 19 jun -wide identification and comparative analysis of albumin family in g li, yiping cao, fang ionary bioinformatics 2017:13 al research | published on 19 jun vation of repeats at the mammalian kcnq1ot1-cdkn1c region suggests a role in genomic de donato, tanveer hussain, hectorina rodulfo, sunday o peters, ikhide g imumorin, bolaji n ionary bioinformatics 2017:13 al research | published on 16 jun ans: an r package to quantify stochastic cell state buder, andreas deutsch, michael seifert, anja voss-böormatics and biology insights 2017:11 al research | published on 16 jun model-based study of the effectiveness of reporting lists of small feature sets using rna-seq kim, ivan ivanov, jianping hua, johanna w lampe, meredith aj hullar, robert s chapkin, edward r informatics 2017:16 ology | published on 12 jun 2017.

Single-molecule, real-time sequencing developed by pacific biosciences offers longer read lengths than the second-generation sequencing (sgs) technologies, making it well-suited for unsolved problems in genome, transcriptome, and epigenetics research. Forthcoming articles must be purchased for the purposes of research, teaching and private study only. Gowda abstract: one of the fundamental components for a wide range of proteomics research is to determine the 3d structure and properties of proteins.

Computational methodology to overcome the challenges associated with the search for specific enzyme targets to develop drugs against leishmania a catharina, carlyle ribeiro lima, alexander franca, ana carolina ramos guimarães, marcelo alves-ferreira, pierre tuffery, philippe derreumaux, nicolas ormatics and biology insights 2017:11 ology | published on 12 jun transfer learning for improved mortality prediction in a data-scarce hospital desautels, jacob calvert, jana hoffman, qingqing mao, melissa jay, grant fletcher, chris barton, uli chettipally, yaniv kerem, ritankar ical informatics insights 2017:9 al research | published on 12 jun l coherence tomography technology and quality improvement methods for optical coherence tomography images of skin: a short adabi, zahra turani, emad fatemizadeh, anne clayton, mohammadreza ical engineering and computational biology 2017:8 review | published on 12 jun ras gene expression levels are influenced by the mutational status of ras genes and both upstream and downstream ras pathway m stephens, ming yi, bailey kessing, dwight v nissley, frank informatics 2017:16 al research | published on 08 jun 2017. Several researches especially in the regulation of blood glucose were carried out and still remained an open challenge. Nas (mirnas) are a class of short non-coding rna molecules that have attracted tremendous attention from the biological and biomedical research communities over the past decade.

S approaches to biology and disease enable translational systems 10, issue 4, august 2012, pages hood | qiang development and application of systems strategies to biology and disease are transforming medical research and clinical practice in an unprecedented rate. Herein, we overview the progress of mirna research related to human diseases, as well as the potential for mirna to becoming the next generation of diagnostics and therapeutics. In this context, the paper is an attempt to highlight the influence of big data in bioinformatics.

Rnbioinformatics has played a significant role in storage and interpretation of the data made available by various wet laboratory experiments, into useful biological information. Yi pan issn online: 1744-5493issn print: 1744-54854 issues per yearsubscription price bioinformatics is an interdisciplinary research field that combines biology, computer science, mathematics and statistics into a broad-based field that will have profound impacts on all fields of biology. Information technology has now reached the modern generation of big data that yields large volumes of structured and unstructured data for the perusal of research people and analysts.

Current strategies for discovery of srnas and their targets usually involve bioinformatics prediction followed by experimental validation, emphasizing a key role for bioinformatics prediction. All articles are listed on pubmed and are freely available via pubmed ical engineering and computational international, peer reviewed, open access journal that covers topics in biomedical engineering, bioinformatics, systems biology, and computational biology, in particular papers using computational methods to address complex problems in today’s medicine and biology. We are at the dawn of predictive, preventive, personalized, and participatory (p4) medicine, the fully implementation of which requires marrying basic and clinical researches through advanced systems thinking and the employment of high-throughput technologies in genomics, proteomics, nanofluidics, single-cell analysis, and computation strategies in a highly-orchestrated discipline we termed translational systems medicine.

For pment and retrospective clinical assessment of a patient-specific closed-form integro-differential equation model of plasma atlas, john k-j li, shawn amin, robert g ical engineering and computational biology 2017:8 al research | published on 26 oct rphism of 11 y chromosome short tandem repeat markers among malaysian sakina mohd yussup, marlia marzukhi, badrul munir md-zain, kamaruddin mamat, farida zuraina mohd ionary bioinformatics 2017:13 al research | published on 17 oct ts into upland cotton ( l. V stabler, eulàlia montell, josep vergés, janet l huebner, virginia byers ker insights 2017:12 report | published on 24 aug zed next-generation sequencing genotype-haplotype calling for genome variability navarro, bruno nevado, porfidio hernández, gonzalo vera, sebastián e ionary bioinformatics 2017:13 al research | published on 24 aug te mitochondrial genomes of the cherskii’s sculpin and siberian taimen reveal genbank entry errors: incorrect species identification and recombinant mitochondrial y s balakirev, pavel a saveliev, francisco j ionary bioinformatics 2017:13 report | published on 24 aug ve multiview nonnegative matrix factorization algorithm for integration of multimodal biomedical a ray, wenke liu, david fenyö. You can get recognition for it by publishing a data note in bmc research cement: we are recruiting new associate are recruiting new associate editors to join our international editorial board, helping to provide expertise on a wide range of subjects within the area of  ed article: ad-libs: inferring ancestry across hybrid genomes using low-coverage sequence study by schaefer et al.

Iman permana maksum, sandy risfi saputra, nenden indrayati, *muhammad yusuf, toto ormatics and biology insights 2017:11 ch proposal | published on 12 sep -set reduction for analysis of major and minor gleason scores based on differential gene-set expressions and biological pathways in prostate dinu, surya poudel, saumyadipta informatics 2017:16 al research | published on 11 sep 2017. All rights > international journal of bioinformatics research and ational journal of bioinformatics research and applicationsthis journal also publishes open access articles editor in chief: prof. Due to multiple advantages of peripheral blood cells over fibroblasts from skin biopsy, the use of blood mononuclear cells (mncs) instead of skin fibroblasts will expedite reprogramming research and broaden the application of reprogramming technology.

Recent advancement in next-generation sequencing techniques and its computational analysis   by khalid raza, sabahuddin ahmad abstract: next generation sequencing (ngs), a recently evolved technology, have served a lot in the research and development sector of our society. Facilitated by high-throughput genomics and bioinformatics in conjunction with traditional molecul ar biology techniques and animal models, mirna research is now positioned to make the transition from laboratories to clinics to deliver profound benefits to public health. This review presents an overview of the bioinformatics resources and approaches for the study of rice- magnaporthe interaction.