Literature review on diabetes mellitus
Previous studies on cadavers have shown microvascular disease affecting the vascular groove, which is responsible for generating endolymph that serves as driving force for mechanical transduction of hair cells involvement of the blood vessels supplying the inner ear and the changes occurring in the vascular striae in patients with diabetes mellitus are facts proven by several authors, who believe that such changes are strong evidence that diabetes mellitus may cause hearing loss ically in the auditory system, it may occur atrophy of spiral ganglion, degeneration of the eighth nerve myelin sheath, decrease on the number of nerve fibers in the spiral blade, or thickening of the capillary walls of the groove vascular and small arteries inside the ear canal ar and nerve tissues have predominant role in auditory function and any disease capable of causing damage its cells has the potential to negatively affect various hearing organs. Use of the auditory brainstem response testing in the clinical evaluation of the patients with diabetes mellitus.
Review of literature on diabetes mellitus
There appears to be a relationship between hearing loss severity and disease progression, and this may be due to microangiopathic disease in the inner ear ic neuropathy, one of the main complications that appear from time of diabetes mellitus chronic evolution, is characterized by progressive degeneration of nerve fibers' axons 24. Some authors refer only that changes in brain cells on some diabetics can result in slower processing of complex sounds, such as of speech ing to the analyzed studies, we can conclude that there is a relation between hearing disorders and diabetes mellitus.
Literature review of diabetes mellitus
It is believed there are several factors that contribute for this association, being needed more studies with more details to establish the true role of these ds: hearing loss; diabetes mellitus; es mellitus is a metabolic disorder, in which there is uncontrolled sugar levels of the organism, affecting all sectors of the body. Prevalence of overweight and obesity among adults with diagnosed diabetes united states, 1988-1994 and 1999-2000"centers for disease control and prevention (cdc) (november 2004) mmwr.
Are there any disturbances in vestibular organ of children and young adults with type i diabetes? Mayfield ja, white n therapy for type 2 diabetes: rescue, augmentation, and replacement of beta-cell function.
Pesquisa do nistagmo/vertigem de posição e avaliação eletronistagmográfica em um grupo de indivíduos portadores de diabetes mellitus tipo i. Dependent on a stable level of glucose in ideal situations, extended periods of hypoglycemia episodes can lead to significant individual neurological alterations findings related to diabetes and hearing loss indicate that diabetes can be considered one of the causes of idiopathic sudden hearing loss 32),(33 since diabetes mellitus is known can cause microvascular damage, as well as other microcirculation disorders involving sudden increase of blood viscosity and thromboembolic episodes 32.
International expert ational expert committee report on the role of the a1c assay in the diagnosis of diabetes. Rosenstock j, lorber dl, gnudi l, howard cp, bilheimer dw, chang pc, et al inhaled insulin plus basal insulin glargine versus twice daily biaspart insulin for type 2 diabetes: a multicentre randomised trial.
Inhaled insulin was licensed for use in 2006 but has been withdrawn from the market because of low ds: type 2 diabetes mellitus, diagnosis, management, newer drugsintroductiondiabetes mellitus (dm) is probably one of the oldest diseases known to man. Although routine clinical tests usually run only in the frequencies of speech, when they identify sensitivity beyond this region (at higher frequencies), we obtain a more complete picture of cochlear status, which may indicate declining hearing in the high frequencies a study by maia and campos, there is no consensus regarding audiological and histopathological aspects of type i diabetes mellitus 21.
The metabolic control of type ii diabetes is usually achieved with diet, physical exercises and/or concomitant use of oral hypoglycemic agents, insulin may be used in the treatment study aims to analyze the relationship between diabetes mellitus, type i and ii, and possible hearing disorders. Screening and diagnosis is still based on world health organization (who) and american diabetes association (ada) criteria which include both clinical and laboratory parameters.
We also believe that there are a number of contributing factors to such an association, and more discerning studies are required to establish the true role of these ering the above, it can be noticed that people with diabetes mellitus are more likely to have hearing loss. Coniff rf, shapiro ja, seaton tb, bray enter, placebo-controlled trial comparing acarbose (bay g 5421) with placebo, tolbutamide, and tolbutamide-plus-acarbose in non-insulin-dependent diabetes mellitus.
Also reported in its research on 59 diabetic patients an increase in latency of the main components of the responses of the brain stem order to investigate the relationship between diabetes mellitus and hearing, another study used the p300 cognitive potential, which has been used as an objective procedure to assess cerebral cognitive function. The cause of neuropathy is still very controversial and may be related to diffuse microangiopathy that would affect nourishment of peripheral nerves ogical association between hearing loss and diabetes mellitus (type i and type ii) has been debated since it was first mentioned by jordan in 1857, being subject of debate and remaining controversial to this day, despite numerous previous studies 8)-( 1864, it was identified the first scientific documentation connecting glucose metabolism disorders to inner ear diseases; observing the relation between sensorineural deafness and diabetes, thus establishing the link between hearing loss and hyperglycemia.
This led to consider that the effect of diabetes on vestibular function could possibly be mediated with diabetic complications such as neuropathy and angiopathy, which are absent at disease onset r, other authors have reported minimal cellular changes and functional impairment of the central labyrinthic pathways as complications of initial diabetes mellitus, with no relation to neuropathy or microangiopathy 9. The pancreas does not produce insulin or produces inefficiently, failing to perform its biological main types of diabetes mellitus are type i and type ii.
Noted that the detection of disorders present in the central nervous system in patients with diabetes mellitus seems to be more sensitive through vestibular assessment than by audiological evaluation. It is characterized by chronic hyperglycemia resulting from disorders in the metabolism of carbohydrates, proteins and fats, due insufficient secretion function and/or insulin absence, as well as for defects of its action on insulin target tissues (liver, muscle and adipose tissues) brazil is quite high the incidence of chronic complications of diabetes.
Hu fb, manson je, stampfer mj, colditz g, liu s, solomon cg, et , lifestyle, and the risk of type 2 diabetes mellitus in women. This review is based on a search of medline, the cochrane database of systemic reviews, and citation lists of relevant publications.
Khz was reported by lisowska l studies have revealed alterations in auditory brainstem evoked potential in individuals with diabetes mellitus showing a prolonged latency of waves iii and v 11), (30. Insulin is always necessary in the treatment of type i diabetes mellitus and should be established as soon as the diagnosis is established 4),( type ii diabetes mellitus results from the action of insulin resistance mechanisms associated with a defect in hormone secretion, corresponding to the most prevalent form of diabetes worldwide 4.